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Table 2 Concordance between radiology, PET and histology

From: Peri-operative chemotherapy in the management of resectable colorectal cancer pulmonary metastases

 

PET positive

PET negative

No PET done

 

n (%)

n (%)

n (%)

Patients*

39 (81)

8 (18)

6 (12)

Resections

48 (86)

8 (14)

16 (22)

Timing of pre-thoracotomy PET

   

Before neoadjuvant chemotherapy

16

3

-

After neoadjuvant chemotherapy

12

1

-

No neoadjuvant chemotherapy

20

4

-

CT identified metastases

   

Median number (range)

1 (1–6)

2 (1–3)

2 (1–11)

PET identified metastases

   

Median number FDG avid (range)

1(1–6)

-

-

Histologically identified metastases #

   

Median number (range)

1 (1–6)

2 (1–4)

1 (1–12)

Median size of largest nodule (range)

15 mm (5–60)

8 mm (3–15)

15 mm (2–25)

Concordance rates on number of metastases +

  

CT + PET

34 (71)

-

-

CT + Histology

28 (61)

4 (50)

10 (71)

PET + Histology

33 (72)

-

-

CT + PET + Histology

26 (57)

-

-

  1. *2 patients had FDG-avid lung lesions prior to one lung resection but no FDG avid lung lesions prior to a subsequent lung resection.
  2. #Histology obtained at time of resection. All lesions considered involved had viable tumour.
  3. +histology not available on 1 PET positive patient, and 2 patients who did not have a PET.