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Table 1 Patient Characteristics at the Time of Primary Diagnosis of Ovarian Cancer

From: LOH at 6q and 10q in fractionated circulating DNA of ovarian cancer patients is predictive for tumor cell spread and overall survival

Patients (%)

Total

63

Age

58 years (range 21 – 81 years)

Tumor stage

FIGO I-II

13 (20.6)

FIGO III

35 (55.6)

FIGO IV

15 (23.8)

Lymph node metastasis

N0

22 (34.9)

N1

20 (31.7)

Nx

21 (33.3)

Tumor grading

I - II

31 (49.2)

III - IV

32 (50.8)

Histologic subtype

serous papillary

 

subtype

50 (79.4)

other subtypes

13 (20.6)

Residual tumor

macroscopic

 

complete resection

30 (47.6)

any residual tumor

33 (52.4)

Survival

OSa

36.5 months (range 1 – 70 months)

Alive

28 (44.4)

Dead

34 (54.0)

DFSb

12 months (range 6 – 48 months)

no relapse

18 (28.6)

relapse

45 (71.4)

Platinum Resistance

Platinum sensitive 54 (85.7)

 

Platinum resistant

9 (14.3)

DTC c

DTC prior to chemotherapy

 

Positive

27 (50.9)

Negative

26 (49.1)

DTC after chemotherapy

 

positive

20 (50.0)

negative

20 (50.0)

  1. aOS, overall survival.
  2. bDFS, disease-free survival.
  3. cDTC, disseminated tumor cells in BM.