Table 1 Correlation of fascin expression with clinico-pathological parameters of the OSCC patients.
From: Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma
| Clinico-pathological parameter | FASCIN | |||||
|---|---|---|---|---|---|---|
| n(131),% | EXPERSSION | P-value | ||||
| Negative | Low | High | ||||
| Age (Years) | < 50 | 75 (57.25) | 15 | 30 | 30 | 0.091* |
| ≥50 | 56 (42.75) | 18 | 25 | 13 | ||
| Sex | Male | 102 (77.87) | 25 | 41 | 36 | 0.524* |
| Female | 29 (22.14) | 8 | 14 | 7 | ||
| Location | Tongue | 61 (46.56) | 17 | 27 | 26 | 0.517* |
| BM | 70 (53.44) | 16 | 28 | 17 | ||
| Thickness | < 2 cm | 92 (70.23) | 25 | 35 | 32 | 0.370* |
| ≥2 cm | 39 (29.77) | 8 | 20 | 11 | ||
| Stages | I/II | 28 (21.38) | 9 | 15 | 4 | 0.041# |
| III/IV | 103 (78.62) | 24 | 40 | 39 | ||
| Tumor Size | T1/T2 | 48 (36.65) | 13 | 23 | 12 | 0.254# |
| T3/T4 | 83 (63.35) | 20 | 31 | 32 | ||
| Node Status | NO | 47 (35.88) | 17 | 22 | 8 | 0.001# |
| N1 | 34 (25.95) | 8 | 14 | 12 | ||
| N2 | 50 (38.17) | 8 | 19 | 23 | ||
| Differentiation | Poor + Moderate | 124 (94.65) | 28 | 53 | 43 | 0.005# |
| well | 7 (5.34) | 5 | 2 | 0 | ||
| Perineural Extension | Yes | 55 (41.98) | 11 | 22 | 22 | 0.538* |
| No | 62 (47.33) | 16 | 27 | 19 | ||
