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Table 5 Final model of the multivariate Cox regression analysis of prognostic factors on overall survival including the interaction term CA19-9 and AB0 blood group of 576 patients with R0/1 pancreatic resection for ductal adenocarcinoma of the pancreas

From: AB0 blood group and prognosis in patients with pancreatic cancer

Parameter Category HR 95% CI P-value
Grading G1 0.41 0.21 – 0.81 0.01
  G2 1   
  G3 1.48 1.19 – 1.84 0.0004
Lymph node status Negative 1   
  Positive 1.52 1.16 – 2.01 0.0026
Age < 70 years 1   
  ≥ 70 years 1.42 1.14 – 1.77 0.003
CA 19–9 [U/ml] / AB0 blood group ≥ 37 / A/AB/B 1   
  < 37 / 0 0.43 0.26 – 0.74 0.002
  ≥ 37 / 0 1.15 0.90 – 1.47 0.24
  < 37 / A/AB/B 0.71 0.52 – 0.96 0.028
  1. A total of 44 patients with missing values were excluded (Likelihood-Ratio Test: p < 0.0001).
  2. HR = hazard ratio, CI = confidence interval.