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Table 5 Final model of the multivariate Cox regression analysis of prognostic factors on overall survival including the interaction term CA19-9 and AB0 blood group of 576 patients with R0/1 pancreatic resection for ductal adenocarcinoma of the pancreas

From: AB0 blood group and prognosis in patients with pancreatic cancer

Parameter

Category

HR

95% CI

P-value

Grading

G1

0.41

0.21 – 0.81

0.01

 

G2

1

  
 

G3

1.48

1.19 – 1.84

0.0004

Lymph node status

Negative

1

  
 

Positive

1.52

1.16 – 2.01

0.0026

Age

< 70 years

1

  
 

≥ 70 years

1.42

1.14 – 1.77

0.003

CA 19–9 [U/ml] / AB0 blood group

≥ 37 / A/AB/B

1

  
 

< 37 / 0

0.43

0.26 – 0.74

0.002

 

≥ 37 / 0

1.15

0.90 – 1.47

0.24

 

< 37 / A/AB/B

0.71

0.52 – 0.96

0.028

  1. A total of 44 patients with missing values were excluded (Likelihood-Ratio Test: p < 0.0001).
  2. HR = hazard ratio, CI = confidence interval.