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Table 2 Results from univariate Cox regression analyses of clinicopathologic parameters including blood group status on overall survival

From: AB0 blood group and prognosis in patients with pancreatic cancer

Parameter

Category

N

Events

HR

95% CI

P-value

Age

<70 years

426

273

1

 

<0.0001

 

≥70 years

194

139

1.54

1.26 – 1.89

 

Sex

Male

336

235

1

 

0.21

 

Female

284

177

0.88

0.73 – 1.07

 

Tumor size

pT1/2

19

13

0.70

0.40 – 1.21

0.19

 

pT3/4

601

399

1

  

Lymph node status

Negative

111

68

1

 

0.0077

 

Positive

509

344

1.42

1.10 – 1.85

 

Procedure

Pancreatico-duodenectomy

440

302

1

 

0.06

 

Distal pancreatectomy

106

58

0.82

0.62 – 1.09

 
 

Total pancreatectomy

74

52

1.33

0.99 – 1.78

 

Grading

G1

19

9

0.38

0.20 – 0.74

<0.0001

 

G2

419

267

1

  
 

G3

178

132

1.51

1.23 – 1.87

 

Resection margin

Negative

329

232

1

 

0.0251

 

Positive

287

177

1.25

1.03 – 1.53

 

CA 19–9 [U/ml]

<37

127

68

1

 

0.0002

 

≥37

453

316

1.65

1.27 – 2.14

 

Blood group

A

324

228

1

 

0.39

 

AB

29

17

0.76

0.47 – 1.25

 
 

B

73

46

0.89

0.65 – 1.23

 
 

O

194

121

0.85

0.68 – 1.06

 

Blood group

A/B/AB

426

291

1

 

0.23

 

O

194

121

0.88

0.71 – 1.09

 

Rhesus factor

Positive

514

340

1

 

0.74

 

Negative

106

72

0.96

0.74 – 1.24

 
  1. Analyses include 620 patients with R0/1 pancreatic resection for ductal adenocarcinoma of the pancreas (7 patients with incomplete follow-up excluded). HR, hazard ratio; CI; confidence interval.