Skip to main content

Table 2 Results from univariate Cox regression analyses of clinicopathologic parameters including blood group status on overall survival

From: AB0 blood group and prognosis in patients with pancreatic cancer

Parameter Category N Events HR 95% CI P-value
Age <70 years 426 273 1   <0.0001
  ≥70 years 194 139 1.54 1.26 – 1.89  
Sex Male 336 235 1   0.21
  Female 284 177 0.88 0.73 – 1.07  
Tumor size pT1/2 19 13 0.70 0.40 – 1.21 0.19
  pT3/4 601 399 1   
Lymph node status Negative 111 68 1   0.0077
  Positive 509 344 1.42 1.10 – 1.85  
Procedure Pancreatico-duodenectomy 440 302 1   0.06
  Distal pancreatectomy 106 58 0.82 0.62 – 1.09  
  Total pancreatectomy 74 52 1.33 0.99 – 1.78  
Grading G1 19 9 0.38 0.20 – 0.74 <0.0001
  G2 419 267 1   
  G3 178 132 1.51 1.23 – 1.87  
Resection margin Negative 329 232 1   0.0251
  Positive 287 177 1.25 1.03 – 1.53  
CA 19–9 [U/ml] <37 127 68 1   0.0002
  ≥37 453 316 1.65 1.27 – 2.14  
Blood group A 324 228 1   0.39
  AB 29 17 0.76 0.47 – 1.25  
  B 73 46 0.89 0.65 – 1.23  
  O 194 121 0.85 0.68 – 1.06  
Blood group A/B/AB 426 291 1   0.23
  O 194 121 0.88 0.71 – 1.09  
Rhesus factor Positive 514 340 1   0.74
  Negative 106 72 0.96 0.74 – 1.24  
  1. Analyses include 620 patients with R0/1 pancreatic resection for ductal adenocarcinoma of the pancreas (7 patients with incomplete follow-up excluded). HR, hazard ratio; CI; confidence interval.