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Table 3 Five-year relative survival of breast cancer patients by age and stage

From: Trends of population-based breast cancer survival in Germany and the US: Decreasing discrepancies, but persistent survival gap of elderly patients in Germany

stage

Germany (Saarland)

US (SEER 9/13 regionsa)

  

1993-96

1997-00

2001-04

2005-08

Δ

p-value

1993-96

1997-00

2001-04

2005-08

Δ

p-value

  

RS

SE

RS

SE

RS

SE

RS

SE

  

RS

SE

RS

SE

RS

SE

RS

SE

  

overall

crude

73.0

1.1

77.1

1.0

80.1

0.9

84.2

0.9

11.2

<0.001

84.1

0.2

86.3

0.2

88.2

0.1

88.6

0.1

4.5

<0.001

 

age std b

72.2

1.3

76.3

1.2

79.0

1.1

82.5

1.0

10.3

<0.001

84.2

0.2

86.3

0.2

88.2

0.2

88.1

0.2

3.9

<0.001

 

stage mix std c

78.8

1.1

82.3

0.9

85.3

0.8

87.9

0.7

9.1

<0.001

84.1

0.2

85.7

0.1

87.7

0.1

88.1

0.1

4.0

<0.001

 

15-49 years

75.4

2.0

78.6

1.8

83.9

1.6

87.7

1.4

12.3

<0.001

82.8

0.3

85.2

0.3

87.3

0.2

89.2

0.2

6.4

<0.001

 

50-69 years

74.7

1.4

79.1

1.3

81.7

1.1

88.6

1.0

14.0

<0.001

85.4

0.2

87.5

0.2

89.8

0.2

90.0

0.2

4.7

<0.001

 

15-69 years

74.9

1.2

78.9

1.0

82.3

0.9

88.4

0.8

13.5

<0.001

84.4

0.2

86.7

0.2

88.9

0.1

89.7

0.1

5.3

<0.001

 

> = 70 years

69.3

2.4

73.6

2.2

75.1

2.1

74.9

2.1

5.6

0.026

83.6

0.4

85.5

0.4

86.5

0.4

85.7

0.4

2.1

0.001

localized

crude

90.7

1.5

93.3

1.2

96.0

1.0

97.5

0.9

6.8

0.002

95.4

0.2

96.1

0.2

97.0

0.2

97.2

0.1

1.8

<0.001

 

age std b

91.4

2.4

94.5

1.9

97.4

1.6

98.7

1.4

7.3

<0.001

95.7

0.2

96.3

0.2

97.3

0.2

97.3

0.2

1.6

<0.001

 

15-49 years

86.9

2.5

92.3

1.9

93.1

1.6

95.3

1.4

8.4

0.011

93.6

0.3

94.1

0.2

95.4

0.2

96.3

0.2

2.7

<0.001

 

50-69 years

91.7

1.8

91.6

1.5

95.4

1.2

98.7

0.9

7.0

0.001

95.4

0.2

96.4

0.2

97.4

0.2

97.6

0.2

2.2

<0.001

 

15-69 years

90.1

1.5

91.8

1.2

94.7

0.9

97.8

0.7

7.7

<0.001

94.8

0.2

95.6

0.1

96.8

0.1

97.2

0.1

2.4

<0.001

 

> = 70 years

93.2

4.6

98.3

3.5

99.9

2.9

96.6

2.9

3.4

0.555

96.7

0.5

97.0

0.4

97.5

0.4

97.4

0.4

0.7

0.290

 

T1 age std b

97.3

4.0

99.3

2.9

99.5

2.4

104.1

1.8

6.8

-

98.8

0.3

99.5

0.2

99.9

0.2

100.4

0.2

1.7

-

 

T2-3 age std b

89.4

3.7

92.1

2.9

93.9

2.4

92.1

2.4

2.7

0.110

86.3

0.6

87.0

0.5

89.7

0.5

89.3

0.5

3.0

<0.001

local/regional spread

crude

65.2

1.8

70.9

1.7

76.4

1.5

81.1

1.5

15.9

<0.001

75.8

0.4

79.0

0.3

83.3

0.3

85.0

0.3

9.2

<0.001

 

age std b

64.0

2.2

70.3

2.0

74.8

1.9

78.6

1.8

14.6

<0.001

75.1

0.4

77.5

0.4

81.7

0.4

82.8

0.4

7.6

<0.001

 

15-49 years

70.7

3.4

71.4

3.1

81.1

2.7

82.6

2.6

11.9

0.004

75.5

0.6

80.2

0.5

83.5

0.4

86.8

0.4

11.3

<0.001

 

50-69 years

65.3

2.5

72.2

2.2

77.6

1.9

86.2

1.7

20.8

<0.001

78.1

0.5

80.6

0.4

86.3

0.3

87.1

0.3

9.1

<0.001

 

15-69 years

66.9

2.0

71.9

1.8

78.6

1.6

85.1

1.4

18.2

<0.001

76.9

0.4

80.4

0.3

85.2

0.3

87.0

0.2

10.0

<0.001

 

> = 70 years

61.1

4.0

68.7

3.7

70.5

3.7

70.8

3.6

9.7

0.084

72.4

0.9

74.3

0.8

76.7

0.8

77.5

0.8

5.1

<0.001

 

T1/2 age std b

73.0

3.1

79.3

2.7

84.4

2.4

85.6

2.2

12.6

<0.001

81.4

0.5

83.6

0.5

87.7

0.4

88.1

0.4

6.7

<0.001

 

T3/4 age std b

47.1

3.6

52.3

3.5

56.2

3.4

64.3

3.2

17.2

<0.001

64.3

1.0

68.1

0.9

71.7

0.8

68.8

0.8

4.5

0.001

distant metastasis

crude

20.2

3.0

21.9

3.0

20.1

2.6

23.0

3.0

2.8

0.111

21.2

0.7

24.1

0.7

27.2

0.7

29.2

0.7

7.9

<0.001

 

age std b

20.3

3.2

22.1

3.0

19.0

2.6

23.7

3.0

3.3

0.106

20.2

0.7

22.5

0.7

25.2

0.7

26.7

0.7

6.5

<0.001

 

15-49 years

11.5

5.8

17.9

8.9

26.9

7.6

29.6

9.1

18.2

0.029

26.8

1.5

31.5

1.4

34.5

1.4

38.8

1.4

11.9

<0.001

 

50-69 years

25.3

4.4

24.7

4.4

23.6

4.0

29.1

4.6

3.8

0.237

21.3

1.0

24.4

1.0

29.0

1.0

30.5

1.0

9.2

<0.001

 

15-69 years

22.0

3.7

23.9

3.9

24.5

3.5

28.5

4.1

6.5

0.058

23.2

0.9

26.9

0.8

30.9

0.8

33.2

0.8

10.0

<0.001

 

> = 70 years

17.2

5.9

19.3

4.7

13.3

3.7

15.3

4.2

−1.9

0.712

17.4

1.1

18.2

1.1

19.0

1.1

19.4

1.1

2.1

0.045

unknown stage

crude

78.4

2.5

81.3

2.8

77.0

3.5

81.4

2.8

3.0

0.381

55.2

1.2

57.7

1.2

55.0

1.4

43.5

1.5

−11.7

<0.001

 

age std b

78.7

2.5

82.1

2.7

77.6

3.2

82.7

2.5

4.0

0.084

55.6

1.3

59.0

1.2

56.1

1.5

45.2

1.6

−10.4

<0.001

  1. Five-year relative survival of female patients with invasive breast cancer (ICD-10 code: C50) from Germany (Saarland) and the US (SEER 9/13 regions) by age and stage for successive calendar periods.
  2. RS: relative survival (period estimate) in %; SE: standard error; std: standardized; Δ : difference of RS between 2005–08 and 1993–96 in % units; a the coverage of SEER program was extended from 9 to 13 registries in 1992; b using weights from the International Cancer Survival Standards [33]; c weights derived from the SEER patients diagnosed 1988–2008.
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