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Table 3 Multivariate Cox Regression Analyses for OS, BCSS and RFS

From: The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

Variables

OS

BCSS

RFS

HR

95% CI

P

HR

95% CI

P

HR

95% CI

P

Age

1.07

1.03-1.10

.000

1.05

1.00-1.09

.03

1.03

1.00-1.07

.07

Lymph node status

         

- vs. +

1.81

0.87-3.82

.12

3.28

1.01-10.63

.05

4.94

1.77-13.80

.002

Tumor size

         

>20 vs. ≤20 mm

1.58

0.65-3.81

.31

2.47

0.60-10.08

.21

2.12

0.72-6.24

.17

Ki67

3.06

1.05-8.93

.04

4.40

0.67-28.82

.12

0.45

0.13-1.53

.20

Grade

0.63

0.27-1.49

.29

0.86

0.20-3.67

.84

2.25

0.78-6.56

.14

HER

3.45

1.16-10.24

.03

5.37

1.61-17.90

.006

4.46

1.63-12.20

.004

ER

0.47

0.17-1.35

.16

0.39

0.11-1.41

.15

0.37

0.12-1.13

.08

CD163 in TS

0.62

0.24-1.58

.32

0.74

0.23-2.38

.61

0.91

0.30-2.72

.86

CD68 in TS

2.96

0.87-10.11

.08

0.12

0.02-0.72

.02

0.29

0.08-1.10

.07

  1. Abbreviations: OS, overall survival; BCSS, breast cancer specific survival; RFS, recurrence free survival; HR, hazard ratio.