Skip to main content

Table 1 Dose and fractionations by site

From: Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): Study protocol for a randomized phase II trial

Tumor Location

Description

Total Dose (Gy)

Number of fractions

Dose per fraction (Gy)

Frequency

Lung

Tumors 3 cm or less surrounded by lung parenchyma

54

3

18

Every second day

Abutting chest wall or >3 cm

55

5

11

Every second day

Within 2 cm of mediastinum or brachial plexus

60

8*

7.5

Every second day

Bone

Any bone except femur

35 Gy

5

7

Daily

Vertebral body: additional options

16-20 Gy OR

1

16-20

Single dose

30 Gy

3

10

Every second day

Brain Metastases

If whole brain treated, then simultaneous boost to each lesion

40 Gy to metastases 20 Gy whole brain (optional)

5

8 Gy to lesion 4 Gy WBRT

Daily

Liver

LRCP site: Dose is based on calculated normal tissue probability of <5%

   

Every second day

Other sites

45-60

3-8

7.5-15

Every second day

Adrenal

 

60 Gy

8

7.5

Every second day

  1. *If esophageal dose constraints cannot be met, 12 fractions should be used.