Figure 9
From: Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
ABCB1 promoter TCF binding sites transcription activity using reporter plasmid pGL3 basic. (A) Scheme of constructs with TCF binding sites. (B) Luciferase activity reporter assay in K562 cells with or without LiCl 10 mM for 24 h. (C) Luciferase activity reporter assay in Lucena cells with or without LiCl 10 mM for 24 h. All luciferase assay results expressed as relative light units (RLU).