Expression of ABCB1 mRNA levels after β-catenin depletion in CML cell lines. (A) β-catenin siRNA in K562 and Lucena cells. (B) Analysis of ABCB1 mRNA levels after β-catenin depletion. Total RNA was isolated and used in RT-qPCR analysis to determine changes in ABCB1 mRNA levels after normalization to β-actin expression. All data were presented as fold inductions relative to control group expression (scrambled). Values represent the means of three independent determinations ± s.d.