Figure 6From: Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia Wnt/β-catenin pathway activation increases ABCB1 expression. Increases in ABCB1 mRNA levels were evaluated after LiCl 10 mM treatment for 24 h. Total RNA was isolated and used in RT-qPCR to determine changes in ABCB1 mRNA levels after normalization to β-actin expression. Values represent the means of three independent determinations ± s.d.Back to article page