Skip to main content

Advertisement

Table 1 VEGF-A, VEGF-R1, and VEGF-R2 expression in normal and IBC cases

From: Tumor stromal vascular endothelial growth factor A is predictive of poor outcome in inflammatory breast cancer

Variable Normal cases (%) IBC cases (%) P**
VEGF-Ac (21,90)    
Low expression 11 (52.4) 89 (98.9)  
High expression 10 (47.6) 1 (1.1) <0.01
VEGF-R1c (25,96)    
Low expression 13 (52.0) 36 (37.5)  
High expression 12 (48.0) 60 (52.5) 0.25
VEGF-R2c* (20,97)    
Low expression 12 (60.0) 32 (33.0)  
High expression 8 (40.0) 65 (67.0) 0.04
VEGF-R2n (20,97)    
Low expression 11 (55.0) 48 (49.5)  
High expression 9 (45.0) 49 (50.5) 0.81
VEGF-As (20,103)    
Low expression 0 39 (37.9)  
High expression 20 (100) 64 (62.1) <0.01
VEGF-R1s (25,96)    
Low expression 14 (56.0) 38 (39.6)  
High expression 11 (44.0) 58 (60.4) 0.18
VEGF-R2s (20,100)    
Low expression 6 (30.0) 48 (48.0)  
High expression 14 (70.0) 52 (52.0) 0.22
  1. * Letter c stands for cytoplasmic, n, nuclear and s, stromal. The numbers of evaluated normal and IBC cases for each variable are shown as superscript in parenthesis; **, Overall P value using Fisher’s exact test. In some cases the tumor epithelial cells were lost during the immunoassay but the stromal component remained and was scored. This explains the discrepancies between the number of cases assessed for the epithelial and stromal contents.