Table 3 Factors associated with LN evaluation (LNE) or use of adjuvant chemotherapy (ACT) in colon cancer practices: uni- and multi-variate models

Evaluation of ≥ 12 LNs*

581 pts

399 pts

ECOG score

0.011

0.014

0

1

ref

1

ref

1

2.02

[1.20-3.41]

2.10

[1.17-3.76]

2 and more

0.81

[0.41-1.60]

0.72

[0.33-1.55]

Tumor location

0.003

0.036

Right

1

ref

1

Left

0.54

[0.36-0.81]

0.58

[0.34-0.97]

Post-operative stage

0.525

0.044

I -II

1

ref

1

ref

III

1.14

[0.76-1.72]

1.73

[1.01-2.95]

Hospital surgery volume

0.001

<0.001

< 30 operations

1

ref

1

ref

≥ 30 operations

2.48

[1.46-4.21]

3.34

[1.70-6.56]

Surgical district

<0.001

0.006

1

1

ref

1.00

ref

2

1.62

[0.90-2.91]

2.07

[0.97-4.42]

3

1.10

[0.48-2.51]

1.30

[0.35-4.88]

4

0.34

[0.18-0.64]

0.38

[0.17-0.85]

5

1.32

[0.73-2.40]

1.54

[0.84-3.40]

Receiving ACT among stage II†

258 pts

255 pts

Age (years)

<0.001

<0.0011

≥75

1

ref

1

ref

< 75

8.68

[4.06-18.54]

28.49

[8.41-96.53]

Local extension

<0.001

<0.001

pT3

1

ref

1

ref

pT4

4.07

[2.12-7.81]

12.30

[3.81-39.75]

Surgery context

<0.001

<0.001

Scheduled

1

ref

1

ref

Emergency

6.89

[3.21-14.73]

25.31

[6.79-94.34]

Hospital of surgery

0.009

0.020

Public

1

ref

1

ref

Private

2.18

[1.21-3.95]

2.61

[1.16-5.87]

Surgical district

0.090

0.036

1

1

ref

1

ref

2

0.53

[0.25-1.13]

0.54

[0.19-1.53]

3

1.89

[0.54-6.56]

1.45

[0.31-6.75]

4

0.28

[0.06-1.29]

0.06

[0.08-0.39]

5

0.57

[0.25-1.29]

0.44

[0.14-1.44]

Not receiving ACT among stage III†

231 pts

226 pts

Age (years)

<0.001

<0.001

< 75

1

ref

1

ref

≥75

8.80

[4.51-17.17]

8.83

[4.34-17.95]

Comorbid conditions

0.001

0.010

None

1

ref

1

ref

One or more

3.46

[1.65-7.27]

3.04

[1.31-7.04]

Hospitals

0.024

0.285

Private

1

ref

1

ref

Public

1.94

[1.09-3.45]

1.48

[0.72-3.03]