TY - JOUR AU - Minami, Seigo AU - Kijima, Takashi AU - Takahashi, Ryo AU - Kida, Hiroshi AU - Nakatani, Takeshi AU - Hamaguchi, Masanari AU - Takeuchi, Yoshiko AU - Nagatomo, Izumi AU - Yamamoto, Suguru AU - Tachibana, Isao AU - Komuta, Kiyoshi AU - Kawase, Ichiro PY - 2012 DA - 2012/07/18 TI - Combination chemotherapy with intermittent erlotinib and pemetrexed for pretreated patients with advanced non-small cell lung cancer: a phase I dose-finding study JO - BMC Cancer SP - 296 VL - 12 IS - 1 AB - Erlotinib and pemetrexed have been approved for the second-line treatment of non-small cell lung cancer (NSCLC). These two agents have different mechanisms of action. Combined treatment with erlotinib and pemetrexed could potentially augment the antitumor activity of either agent alone. In the present study, we investigated the safety profile of combined administration of the two agents in pretreated NSCLC patients. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-12-296 DO - 10.1186/1471-2407-12-296 ID - Minami2012 ER -