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Table 1 Ratio of HIF-α to PHDs incidence in solid tumor specimens

From: Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

Incidence ratio@

 

HIF-1α/PHD2

HIF-1α/PHD3

HIF-2α/PHD2

HIF-2α/PHD3

ccRCC

1.29*

-

2.22*

-

H & N

0.22

1.25

0.13

0.72

Colorectal

0.15

0.26

0.18

0.32

  1. @Incidence ratio was calculated by dividing incidence of HIF-α by the incidence of PHD2 or PHD3. *P < 0.01.