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Figure 6 | BMC Cancer

Figure 6

From: Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells

Figure 6

ICI 182780 is required for the efficient suppression of ER-dependent endogenous transcripts during serum starvation. Exponentially growing MCF-7 cells (shaded bars) and cells incubated for 48 h in serum- and phenol red-free medium, with or without ICI 182780 (10 nM), were analyzed by RT-QPCR for the ER-inducible pS2 and progesterone receptor (PR) mRNAs. The values of ΔΔCT (means of two independent experiments performed in duplicate) in relation to the exponentially growing cells are presented.

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