From: Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer
Protein expression cohort 1 | Protein expression cohort 2 | |||||
---|---|---|---|---|---|---|
n (%) | low 235(90.4) | high 25(9.6) | p-value | low 291(92.1) | high 25(7.9) | p-value |
Age | ||||||
<=75 | 130(55.3) | 16(64.0) | 0.406 | 166(57.0) | 137(69.9) | 0.625 |
>75 | 105(44.7) | 9(36.0) | 125(43.0) | 59(30.1) | ||
Gender | ||||||
Female | 116(52.2) | 14(65.2) | 0.528 | 143(49.1) | 13(52.0) | 0.784 |
Male | 119(47.8) | 11(34.8) | 148(50.9) | 12(48.0) | ||
T stage | ||||||
1, 2 | 78(33.2) | 8(32.0) | 0.979 | 52(17.9) | 1(4.0) | 0.017 |
3 | 124(52.8) | 14(56.0) | 193(66.3) | 15(60.0) | ||
4 | 28(11.9) | 3(12.0) | 46(15.8) | 9(36.0) | ||
Missing | 5(2.1) | |||||
N stage | ||||||
0 | 154(65.5) | 9(36.0) | 0.005 | 179(61.7) | 5(20.0) | <0.001 |
1 | 53(22.6) | 8(32.0) | 57(19.7) | 8(32.0) | ||
2 | 23(9.8) | 7(28.0) | 54(18.6) | 12(48.0) | ||
Missing | 5 (2.1) | 1 (4.00) | ||||
M stage | ||||||
0 | 201(85.5) | 19(87.0) | 0.150 | 262(90.0) | 14(56.0) | <0.001 |
1 | 31(13.2) | 6(13.0) | 29(10.0) | 11(44.0) | ||
Missing | 3(1.3) | |||||
Location | ||||||
Colon | 189(78.3) | 22(78.3) | 0.376 | 194(66.7) | 16(64.0) | 0.057 |
Rectum | 45(21.7) | 3(21.7) | 97 (33.3) | 9(36.0) | ||
Missing | 1 | |||||
Differentiation grade | ||||||
High-intermediate | 181(80.4) | 13(78.3) | 0.006 | 233(80.1) | 15(60.0) | 0.019 |
Low | 54(19.6) | 12(21.7) | 58(19.9) | 10(40.0) | ||
Vascular invasion | ||||||
Absent | 126(53.6) | 6(95.7) | 0.003 | 258(88.7) | 18(72.0) | 0.016 |
Present | 101(43.0) | 19(4.3) | 33(11.3) | 7(28.0) | ||
Missing | 8(3.4) | |||||
Neural invasion | ||||||
Absent | N/A | N/A | 286(98.3) | 22(88) | 0.002 | |
Present | 5(1.7) | 3(12) |