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Table 1 Association between PODXL protein expression and clinicopathological parameters

From: Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

 

Protein expression cohort 1

Protein expression cohort 2

n (%)

low 235(90.4)

high 25(9.6)

p-value

low 291(92.1)

high 25(7.9)

p-value

Age

 <=75

130(55.3)

16(64.0)

0.406

166(57.0)

137(69.9)

0.625

 >75

105(44.7)

9(36.0)

 

125(43.0)

59(30.1)

 

Gender

 Female

116(52.2)

14(65.2)

0.528

143(49.1)

13(52.0)

0.784

 Male

119(47.8)

11(34.8)

 

148(50.9)

12(48.0)

 

T stage

 1, 2

78(33.2)

8(32.0)

0.979

52(17.9)

1(4.0)

0.017

 3

124(52.8)

14(56.0)

 

193(66.3)

15(60.0)

 

 4

28(11.9)

3(12.0)

 

46(15.8)

9(36.0)

 

 Missing

5(2.1)

     

N stage

 0

154(65.5)

9(36.0)

0.005

179(61.7)

5(20.0)

<0.001

 1

53(22.6)

8(32.0)

 

57(19.7)

8(32.0)

 

 2

23(9.8)

7(28.0)

 

54(18.6)

12(48.0)

 

 Missing

5 (2.1)

1 (4.00)

    

M stage

 0

201(85.5)

19(87.0)

0.150

262(90.0)

14(56.0)

<0.001

 1

31(13.2)

6(13.0)

 

29(10.0)

11(44.0)

 

 Missing

3(1.3)

     

Location

 Colon

189(78.3)

22(78.3)

0.376

194(66.7)

16(64.0)

0.057

 Rectum

45(21.7)

3(21.7)

 

97 (33.3)

9(36.0)

 

 Missing

1

     

Differentiation grade

 High-intermediate

181(80.4)

13(78.3)

0.006

233(80.1)

15(60.0)

0.019

 Low

54(19.6)

12(21.7)

 

58(19.9)

10(40.0)

 

Vascular invasion

 Absent

126(53.6)

6(95.7)

0.003

258(88.7)

18(72.0)

0.016

 Present

101(43.0)

19(4.3)

 

33(11.3)

7(28.0)

 

 Missing

8(3.4)

     

Neural invasion

 Absent

N/A

N/A

 

286(98.3)

22(88)

0.002

 Present

   

5(1.7)

3(12)

 
  1. N/A – not analyzed
  2. χ2-test of association was used for 2x2 tables and χ2-test for linear trend for tables with more than two rows and/or columns. The number of cases with missing data is given for some variables, but these are not included in the analyses.