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Table 1 Association between PODXL protein expression and clinicopathological parameters

From: Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer

  Protein expression cohort 1 Protein expression cohort 2
n (%) low 235(90.4) high 25(9.6) p-value low 291(92.1) high 25(7.9) p-value
Age
 <=75 130(55.3) 16(64.0) 0.406 166(57.0) 137(69.9) 0.625
 >75 105(44.7) 9(36.0)   125(43.0) 59(30.1)  
Gender
 Female 116(52.2) 14(65.2) 0.528 143(49.1) 13(52.0) 0.784
 Male 119(47.8) 11(34.8)   148(50.9) 12(48.0)  
T stage
 1, 2 78(33.2) 8(32.0) 0.979 52(17.9) 1(4.0) 0.017
 3 124(52.8) 14(56.0)   193(66.3) 15(60.0)  
 4 28(11.9) 3(12.0)   46(15.8) 9(36.0)  
 Missing 5(2.1)      
N stage
 0 154(65.5) 9(36.0) 0.005 179(61.7) 5(20.0) <0.001
 1 53(22.6) 8(32.0)   57(19.7) 8(32.0)  
 2 23(9.8) 7(28.0)   54(18.6) 12(48.0)  
 Missing 5 (2.1) 1 (4.00)     
M stage
 0 201(85.5) 19(87.0) 0.150 262(90.0) 14(56.0) <0.001
 1 31(13.2) 6(13.0)   29(10.0) 11(44.0)  
 Missing 3(1.3)      
Location
 Colon 189(78.3) 22(78.3) 0.376 194(66.7) 16(64.0) 0.057
 Rectum 45(21.7) 3(21.7)   97 (33.3) 9(36.0)  
 Missing 1      
Differentiation grade
 High-intermediate 181(80.4) 13(78.3) 0.006 233(80.1) 15(60.0) 0.019
 Low 54(19.6) 12(21.7)   58(19.9) 10(40.0)  
Vascular invasion
 Absent 126(53.6) 6(95.7) 0.003 258(88.7) 18(72.0) 0.016
 Present 101(43.0) 19(4.3)   33(11.3) 7(28.0)  
 Missing 8(3.4)      
Neural invasion
 Absent N/A N/A   286(98.3) 22(88) 0.002
 Present     5(1.7) 3(12)  
  1. N/A – not analyzed
  2. χ2-test of association was used for 2x2 tables and χ2-test for linear trend for tables with more than two rows and/or columns. The number of cases with missing data is given for some variables, but these are not included in the analyses.