|  | Controls (n = 378) | Cases (n = 359) |  |  | ||
---|---|---|---|---|---|---|---|
Variables | Â | n | % | n | % | ORa (95% CI) | ORb (95% CI) |
Estradiol + rs1256049 |  |  |  |  |  |  | |
Low | CT/TT | 127 | 33.8 | 96 | 27.3 | 1.0 | 1.0 |
 | CC | 80 | 21.3 | 87 | 24.7 | 1.6 (1.0–2.4) | 1.7 (1.1–2.6) |
High | CT/TT | 109 | 29.0 | 101 | 28.7 | 1.5 (1.0–2.3) | 1.2 (0.8–1.9) |
 | CC | 60 | 16.0 | 68 | 19.3 | 1.6 (1.0–2.5) | 1.4 (0.8–2.3) |
Estradiol + rs4986938 |  |  |  |  |  |  | |
Low | CC | 162 | 43.4 | 144 | 40.6 | 1.0 | 1.0 |
 | CT/TT | 42 | 11.3 | 43 | 12.1 | 1.1 (0.7–1.9) | 1.1 (0.6–1.9) |
High | CC | 136 | 36.5 | 113 | 31.8 | 1.0 (0.7–1.4) | 0.8 (0.6–1.2) |
 | CT/TT | 33 | 8.9 | 55 | 15.5 | 2.3 (1.4–3.9) | 1.6 (0.9–2.9) |