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Table 1 Selected basic patient characteristics*

From: XELIRI-bevacizumab versus FOLFIRI-bevacizumab as first-line treatment in patients with metastatic colorectal cancer: a Hellenic Cooperative Oncology Group phase III trial with collateral biomarker analysis

 

Group A

Group B

(XELIRI-Bev)

(FOLFIRI-Bev)

N = 143

N = 142

Age

Median (range)

66 (28–84)

66 (32–80)

 

N (%)

N (%)

<60

40 (28)

44 (31)

≥60

103 (72)

98 (69)

Gender

Male

79 (55)

92 (65)

Female

64 (45)

50 (35)

PS (ECOG)

0

92 (64)

94 (66)

1

37 (26)

40 (28)

2

12 (8)

6 (4)

Missing data

2 (2)

2 (2)

Primary location

Colon

98 (68)

85 (60)

Rectum

35 (25)

44 (31)

Rectosigmoid

3 (2)

8 (6)

Rectosigmoid and cecum

1 (1)

Misssing data

6 (4)

5 (3)

Stage at diagnosis

I

2 (1)

3 (2)

II

5 (4)

11 (8)

III

23 (16)

26 (18)

IV

107 (75)

90 (63)

Missing data

6 (4)

12 (9)

Previous adjuvant chemotherapy

No

114 (80)

112 (79)

Yes

27 (19)

27 (19)

Missing data

2 (1)

3 (2)

Previous surgery

114 (80)

123 (87)

Symptomatic disease

Yes

70 (49)

66 (46)

No

56 (39)

54 (38)

Missing data

17 (12)

22 (16)

Organs involved

Liver

103 (72)

101 (71)

Lung

51 (36)

39 (28)

Other

54 (38)

61 (43)

Number of organs involved

1

84 (59)

85 (60)

2

39 (27)

43 (30)

≥3

19 (13)

14 (10)

Missing data

1 (1)

  1. *Pearson chi-square and Fisher’s exact tests were applied to compare patient characteristics (all p values above 0.05).