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Table 1 Impact of the potential prognostic factors on functional outcome

From: Prognostic factors for different outcomes in patients with metastatic spinal cord compression from cancer of unknown primary

 

Improvementn (%)

No changen (%)

Deterioration n (%)

p

Age

   ≤65 years (n = 85)

9 (11)

53 (62)

23 (27)

 

   >65 years (n = 90)

12 (13)

43 (48)

35 (39)

0.54

Gender

   Female (n = 53)

8 (15)

27 (51)

18 (34)

 

   Male (n = 122)

13 (11)

69 (57)

40 (33)

0.42

ECOG performance score

   2 (n = 49)

10 (20)

29 (59)

10 (20)

 

   3-4 (n = 126)

11 (9)

67 (53)

48 (38)

0.25

Number of involved vertebrae

   1-2 (n = 55)

8 (15)

35 (64)

12 (22)

 

   ≥3 (n = 120)

13 (11)

61 (51)

46 (38)

0.84

Ambulatory status prior to RT

   Not Ambulatory    (n = 89)

9 (10)

46 (52)

34 (38)

 

   Ambulatory (n = 86)

12 (14)

50 (58)

24 (28)

0.21

Other bone metastases

   No (n = 65)

11 (17)

39 (60)

15 (23)

 

   Yes (n = 110)

10 (9)

57 (52)

43 (39)

0.46

Visceral metastases

   No (n = 86)

15 (17)

34 (40)

37 (43)

 

   Yes (n = 89)

6 (7)

62 (70)

21 (24)

0.030

Time developing motor deficits

   1-7 days (n = 88)

4 (5)

38 (43)

46 (52)

 

   >7 days (n = 87)

17 (20)

58 (67)

12 (14)

<0.001

Radiation schedule

   Short-course RT    (n = 90)

7 (8)

60 (67)

23 (26)

 

   Longer-course RT    (n = 85)

14 (16)

36 (42)

35 (41)

0.86

Entire cohort (n = 175)

21 (12)

96 (55)

58 (33)

 
  1. The p-values were obtained from the multivariate analysis performed with the ordered-logit model.