Table 2 Patients characteristics
| Â | Â | Patients (n) | Percentage |
|---|---|---|---|
Sex | Men | 43 | 48.9% |
Women | 45 | 51.1% | |
Age (years) | Mean (min-max) | 70.9 | (25–93) |
RIN | Mean (min-max) | 8.9 | (7.5-10) |
Duke's Stage | A | 24 | 27.27% |
B | 26 | 29.55% | |
C | 19 | 21.59% | |
D | 19 | 21.59% | |
MSS/MSI | MSS | 79 | 89.8% |
MSI | 9 | 10.2% | |
Location | Ascending C. | 33 | 37.5% |
Sigmoid | 32 | 36.4% | |
Rectum | 14 | 15.9% | |
Descending C. | 3 | 3.4% | |
| Â | Transverse C. | 6 | 6.8% |
Mut. PI3K | Exon 9 | 12 | 13.6% |
Exon 20 | 8 | 9.1% | |
Wild Type | 68 | 77.3% | |
Mut. B-Raf | Mutated | 8 | 9.1% |
Wild Type | 80 | 90.9% | |
Mut. K-ras | Codon 12 | 28 | 31.8% |
Codon 13 | 6 | 6.8% | |
Wild Type | 54 | 61.4% | |
Histologic grade | Undifferentiated | 1 | 1.1% |
| Â | Poorly diff. | 5 | 5.7% |
| Â | Moderately diff. | 51 | 58.0% |
| Â | Well diff. | 31 | 35.2% |
Histologic subtypes | Conventional | 78 | 88.64% |
| Â | Mucinous | 10 | 11.36% |
Tumoral margin | Expansive | 16 | 18.18% |
| Â | Infiltrative | 61 | 69.32% |
| Â | Mixed | 11 | 12.50% |
Vascular invasion | Yes | 33 | 37.50% |
| Â | No | 55 | 62.50% |
Perineural invasion | Yes | 8 | 9.09% |
| Â | No | 80 | 90.91% |
Lymphocyte infiltration | Absent | 53 | 60.23% |
| Â | Low | 15 | 17.05% |
Medium | 17 | 19.32% | |
| Â | High | 3 | 3.41% |