Figure 10From: TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells Scheme of the molecular mechanism proposed for TGF-β1 action as a common regulator of MMPs (MMP-2 and MMP-9) and their inhibitors (TIMP-2 and RECK), through ERK1/2 and p38 MAPK pathways, in MDA-MB-231 cell line. The dashed lines indicate regulations suggested by preliminary experiments.Back to article page