Figure 1From: TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells Relative mRNA expression levels of MMPs and MMPs inhibitors in breast cancer cell lines. Total RNA from a panel of five human breast cancer cell lines displaying different invasion and metastatic potentials were used to analyze the mRNA expression levels of MMPs (MMP-2, MMP-9 and MMP-14) and MMPs inhibitors (TIMP-1, TIMP-2, TIMP-3 and RECK) by qRT-PCR. Results are presented as means ± standard errors from three independent experiments, each measured in triplicate. *, p < 0.05, **, p < 0.01 and *** p < 0.001, all versus control (MCF-7).Back to article page