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Table 3 Correlation of Cyclin A1 expression in immunohistochemistry with clinicopathological characteristics in controls (tonsils)

From: Cyclin A1 shows age-related expression in benign tonsils, HPV16-dependent overexpression in HNSCC and predicts lower recurrence rate in HNSCC independently of HPV16

Clinicopathological parameter N Performed Statistic Subgroups P
Age [y] 74 Spearman Rank Order σ = −0.512 0.000004
Sex 74 Mann–Whitney Rank Sum male vs. female 0.899
Nicotine abuse 74 Mann–Whitney Rank Sum nicotine vs. no nicotine 0.012
Alcohol abuse 74 Mann–Whitney Rank Sum alcohol vs. no alcohol 0.160
P16 Expression 74 Spearman Rank Order σ = 0.336 0.005
P53 Expression 74 Spearman Rank Order σ = 0.419 0.0002
Cyclin A1 Methylation 12 Mann–Whitney Rank Sum methylated vs. non-methylated 0.386
  1. N: number of available samples; Age in years [y].