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Table 2 QUADAS-2 quality items results

From: Does risk for ovarian malignancy algorithm excel human epididymis protein 4 and ca125 in predicting epithelial ovarian cancer: A meta-analysis

Study ID Risk of Bias Concerns Regarding Applicability
  PATIENT SELECTION INDEX TEST REFERENCE STANDARD FLOW & TIMING PATIENT SELECTION INDEX TEST REFERENCE STANDARD
       HE4 CA125 ROMA  
Abdel-Azeez et al., 2010 ? ? ? ? -
Bandiera et al., 2011 ? ?
Chang et al., 2011 ? ? - ?
Holcomb et al., 2011 ? -
Jacob et al., 2011 ? ?
Kim et al., 2011
Montagnana et al., 2011 ?
Moore et al., 2008 ? -
Moore et al. 2009 ?
Moore et al., 2011 ?
Van Gorp et al. 2011
  1. ROMA: Risk of Ovarian Malignancy Algorithm; HE4: Human Epididymis Protein 4; CA125: Cancer Antigen 125.
  2. ☺: low risk; ☻: high risk; ?: unclear risk.