Summary receiver operating characteristic (SROC) curves for ROMA, HE4 and CA125 to predict EOC. Results of bivariate analysis: estimates of each studies (the squares) and SROCs (solid line) for ROMA (black), HE4 (red) and CA125 (green) were shown. Each study is represented by each square in the meta-analysis. The size of the square indicates the size of each study. The AUCs and 95% CIs of ROMA, HE4 and CA125 are 0.92 (0.86- 0.97), 0.95 (0.92- 0.98) and 0.88 (0.81- 0.96), respectively.