Table 3 Groups of tobacco-related cancer sites with mutually significantly increased risk of subsequent primary cancer valid for at least one sex and split into pairs (Bavaria; 2002–2008; for each pair, the respective identified sex is given as well as known shared risk factors; data sources,[17–21])
From: Risk of tobacco-related multiple primary cancers in Bavaria, Germany
Group | Pair of cancer types with mutually significantly elevated risk of subsequent primary cancer | Sex | Shared risk factors in addition to tobacco smoking |
|---|---|---|---|
1 | mouth/pharynx – oesophagus | m,f | alcohol consumption, low fruit and vegetable intake, low socioeconomic status |
mouth/pharynx – larynx | m,f | alcohol consumption, low fruit and vegetable intake | |
mouth/pharynx – lung/bronchus | m,f | low fruit and vegetable intake | |
oesophagus – larynx | m | alcohol consumption, low fruit and vegetable intake | |
larynx – lung/bronchus | m | low fruit and vegetable intake | |
lung/bronchus – oesophagus | m | low fruit and vegetable intake | |
2 | lung/bronchus – kidney | m,f | - |
kidney – bladder | m,f | - | |
bladder – lung/bronchus | m,f | - | |
3 | bladder – lung/bronchus | m,f | - |
lung/bronchus – urinary tract | f | - | |
urinary tract – bladder | f | ionizing radiation, heavy use of phenacetin-containing analgesics | |
4 | mouth/pharynx – colon/rectum | m | alcohol consumption, low fruit and vegetable intake |
5 | stomach – pancreas | m,f | obesity |