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Table 3 Groups of tobacco-related cancer sites with mutually significantly increased risk of subsequent primary cancer valid for at least one sex and split into pairs (Bavaria; 2002–2008; for each pair, the respective identified sex is given as well as known shared risk factors; data sources,[1721])

From: Risk of tobacco-related multiple primary cancers in Bavaria, Germany

Group Pair of cancer types with mutually significantly elevated risk of subsequent primary cancer Sex Shared risk factors in addition to tobacco smoking
1 mouth/pharynx – oesophagus m,f alcohol consumption, low fruit and vegetable intake, low socioeconomic status
  mouth/pharynx – larynx m,f alcohol consumption, low fruit and vegetable intake
  mouth/pharynx – lung/bronchus m,f low fruit and vegetable intake
  oesophagus – larynx m alcohol consumption, low fruit and vegetable intake
  larynx – lung/bronchus m low fruit and vegetable intake
  lung/bronchus – oesophagus m low fruit and vegetable intake
2 lung/bronchus – kidney m,f -
  kidney – bladder m,f -
  bladder – lung/bronchus m,f -
3 bladder – lung/bronchus m,f -
  lung/bronchus – urinary tract f -
  urinary tract – bladder f ionizing radiation, heavy use of phenacetin-containing analgesics
4 mouth/pharynx – colon/rectum m alcohol consumption, low fruit and vegetable intake
5 stomach – pancreas m,f obesity