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Table 2 Unadjusted hazard ratios and 95% CI for overall and Gleason-specific prostate cancer by cholesterol quintiles among Midspan subjects who survived until 1st January 1997. N = 6486.

From: Cholesterol and the risk of grade-specific prostate cancer incidence: evidence from two large prospective cohort studies with up to 37 years' follow up

Ā Ā 

All Prostate cancer

Gleason < 7

Gleason 7

Gleason ā‰„8

Unknown

Cholesterol (mmol/L) quintiles

Ā 

(n)

Hazard Ratio (95%CI)

%

(n)

Hazard Ratio (95%CI)

%

(n)

Hazard Ratio (95%CI)

%

(n)

Hazard Ratio (95%CI)

%

(n)

Hazard Ratio (95%CI)

< 5.05

Ā 

1,384

(61)

Ā 

1

24.6

(15)

Ā 

1

21.3

(13)

Ā 

1

27.9

(17)

Ā 

1

26.2

(16)

Ā 

1

5.06 - < 5.57

1,308

(51)

0.87

(0.60, 1.26)

17.6

(9)

0.62

(0.27,1.41)

13.7

(7)

0.54

(0.22,1.36)

37.3

(19)

1.18

(0.61, 2.27)

31.4

(16)

1.04

(0.52, 2.09)

5.58 - < 6.09

1,425

(65)

1.03

(0.72, 1.46)

26.2

(17)

1.1

(0.56,2.27)

12.3

(8)

0.59

(0.24,1.42)

26.2

(30)

1.70

(0.93, 3.07)

15.4

(10)

0.59

(0.27, 1.31)

6.1 - < 6.69

1,159

(71)

1.36

(0.97, 1.92)

16.9

(12)

0.96

(0.45,2.05)

18.3

(13)

1.14

(0.53,2.47)

46.5

(33)

2.28

(1.27, 4.10)

18.3

(13)

0.95

(0.46, 1.98)

ā‰„6.7

Ā 

1,210

(59)

1.09

(0.76, 1.57)

18.6

(11)

0.83

(0.38,1.81)

27.1

(16)

1.35

(0.65,2.81)

33.9

(20)

1.34

(0.70, 2.57)

20.3

(12)

0.85

(0.40, 1.80)

  1. Univariate hazard ratios and 95% confidence intervals were estimated within a model employing age as time-scale