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Table 2 Unadjusted hazard ratios and 95% CI for overall and Gleason-specific prostate cancer by cholesterol quintiles among Midspan subjects who survived until 1st January 1997. N = 6486.

From: Cholesterol and the risk of grade-specific prostate cancer incidence: evidence from two large prospective cohort studies with up to 37 years' follow up

   All Prostate cancer Gleason < 7 Gleason 7 Gleason ≥8 Unknown
Cholesterol (mmol/L) quintiles   (n) Hazard Ratio (95%CI) % (n) Hazard Ratio (95%CI) % (n) Hazard Ratio (95%CI) % (n) Hazard Ratio (95%CI) % (n) Hazard Ratio (95%CI)
< 5.05   1,384 (61)   1 24.6 (15)   1 21.3 (13)   1 27.9 (17)   1 26.2 (16)   1
5.06 - < 5.57 1,308 (51) 0.87 (0.60, 1.26) 17.6 (9) 0.62 (0.27,1.41) 13.7 (7) 0.54 (0.22,1.36) 37.3 (19) 1.18 (0.61, 2.27) 31.4 (16) 1.04 (0.52, 2.09)
5.58 - < 6.09 1,425 (65) 1.03 (0.72, 1.46) 26.2 (17) 1.1 (0.56,2.27) 12.3 (8) 0.59 (0.24,1.42) 26.2 (30) 1.70 (0.93, 3.07) 15.4 (10) 0.59 (0.27, 1.31)
6.1 - < 6.69 1,159 (71) 1.36 (0.97, 1.92) 16.9 (12) 0.96 (0.45,2.05) 18.3 (13) 1.14 (0.53,2.47) 46.5 (33) 2.28 (1.27, 4.10) 18.3 (13) 0.95 (0.46, 1.98)
≥6.7   1,210 (59) 1.09 (0.76, 1.57) 18.6 (11) 0.83 (0.38,1.81) 27.1 (16) 1.35 (0.65,2.81) 33.9 (20) 1.34 (0.70, 2.57) 20.3 (12) 0.85 (0.40, 1.80)
  1. Univariate hazard ratios and 95% confidence intervals were estimated within a model employing age as time-scale