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Table 1 Correlations between the mRNA expression of coactivators, HER growth factor receptors, Ets-2 and ERα

From: Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer

 

SRC-1

SRC-2/TIF-2

SRC-3/AIB1

HER-1

HER-2

HER-3

HER-4

Ets-2

 

r

P

r

P

r

P

r

P

r

P

r

P

r

P

r

P

SRC-2/TIF-2

0.741

<0.001**

-

-

            

SRC-3/AIB1

0.141

0.53

0.483

0.023*

-

-

          

HER-1

0.260

0.242

0.335

0.128

0.293

0.186

-

-

        

HER-2

0.659

0.001**

0.714

<0.001**

0.355

0.105

0.477

0.025*

-

-

      

HER-3

0.395

0.069

0.467

0.028*

0.071

0.755

0.354

0.106

0.579

0.005**

-

-

    

HER-4

0.475

0.026*

0.596

0.003**

0.717

<0.001**

0.224

0.316

0.482

0.023*

0.280

0.208

-

-

  

Ets-2

0.313

0.156

0.495

0.019*

0.778

<0.001**

0.214

0.339

0.554

0.007**

0.149

0.510

0.789

<0.001**

-

-

ERα

0.320

0.146

0.338

0.124

-0.015

0.946

0.099

0.662

0.389

0.074

0.088

0.699

0.235

0.291

0.264

0.236

  1. Spearman’s nonparametric test. Correlation coefficients (r) with P-values are presented in the table. Significant correlations are indicated by italics and * = P < 0.05 or ** = P < 0.01