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Figure 5 | BMC Cancer

Figure 5

From: The application of nonsense-mediated mRNA decay inhibition to the identification of breast cancer susceptibility genes

Figure 5

Pedigree of Family B (A) and sequencing chromatogram of PPARGC1A IVS-7delT variant (B). GINI experiments were performed on the LCLs derived from individuals marked with red circles. The red coloured numbers correspond to the person number in Figure 4. Upward arrows indicate individuals that showed stabilisation of the PPARGC1A transcript. The IVS-7delT variant (B) is located seven base pairs upstream from the start of exon 6 and was found in both affected and unaffected members of Family B as indicated by stars in the pedigree.

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