The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization

Lo, Fang-Yi; Chang, Jer-Wei; Chang, I-Shou; Chen, Yann-Jang; Hsu, Han-Shui; Huang, Shiu-Feng Kathy; Tsai, Fang-Yu; Jiang, Shih Sheng; Kanteti, Rajani; Nandi, Suvobroto; Salgia, Ravi; Wang, Yi-Ching

doi:10.1186/1471-2407-12-235

Table 4 Candidate genes in lung cancer

From: The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization

Gene name^a	a-CGH (%)	Gene name^a	a-CGH (%)	Gene name^a	a-CGH (%)
A. Asian
ACAA1	Loss: 65	FRS2	Loss: 55	RPSA	Loss: 68
ALDH18A1	Gain: 58	HADHA	Loss: 63	RYBP*	Gain: 73
ANKRD2	Gain: 58	HELLS	Gain: 58	SCGN	Loss: 80
APOB	Loss: 58	HK1	Gain: 55	SERPINF1	Gain: 60
ARHGAP19	Gain: 60	ING4	Gain: 65	SNRK	Loss: 65
AVPI1	Gain: 58	ITGA9	Loss: 65	SPG20	Loss: 65
AXUD1	Loss: 65	LBH	Loss: 63	SUCLG2	Gain: 73
BLNK	Gain: 58	LRIG1	Gain: 73	TNFRSF1A	Gain: 65
CCK	Loss: 68	LTBR	Gain: 65	TRPC4	Loss: 65
CCNA1	Loss: 80	LYZ	Loss: 55	UBE1C*	Gain: 73
CRK	Gain: 60	MAGI1	Gain: 73	UCN	Loss: 63
CTDSPL	Loss: 65	MITF*	Gain: 73	VAMP1	Gain: 65
CX3CR1	Loss: 65	MLH1	Loss: 65	YWHAE	Gain: 60
CYP2C19	Gain: 58	MNT	Gain: 60	ZDHHC16	Gain: 58
DLEC1	Loss: 65	MyD88	Loss: 65	ZNF322A*	Gain: 70
FKBP4	Gain: 65	PAFAH1B1*	Gain: 60	ZNF35	Loss: 65
FOSL2	Loss: 63	PDCD6IP	Loss: 65	ZNF384	Gain: 65
FOXM1	Gain: 65	RAD51AP1	Gain: 65
FRAT2	Gain: 58	RPA1	Gain: 60
B. Caucasian
Gene name ^a	a-CGH (%)	Gene name ^a	a-CGH (%)	Gene name ^a	a-CGH (%)	Gene name ^a	a-CGH (%)
ABT1	Gain: 60	HESX1	Gain: 50	PROK2	Gain: 70	VGLL3	Loss: 70
ARF4	Gain: 50	HIST1H1A	Gain: 60	PUM2	Gain: 55	WAPAL	Loss: 70
ASPA	Gain: 65	HIST1H1C	Gain: 50	RAD18	Gain: 50	XDH*	Loss: 50
CAV3	Gain: 50	HIST1H1D	Gain: 50	RBBP7	Gain: 50	YY2	Gain: 60
CCR1	Gain: 60	HIST1H1E	Gain: 50	REPS2	Gain: 50	ZBTB47	Gain: 55
CCR5	Gain: 60	HIST1H1T	Gain: 50	RhoB	Gain: 55	ZFX	Gain: 50
CD2AP	Gain: 50	HIST1H4B	Gain: 60	ROBO1	Gain: 65	ZNF165	Gain: 55
CDCP1	Gain: 60	HIST1H4F	Gain: 50	ROBO2	Gain: 70	ZNF167	Gain: 60
CGGBP1	Loss: 80	LMCD1	Gain: 50	RYBP*	Gain: 70	ZNF184	Gain: 50
CLEC3B	Gain: 60	LTF	Gain: 60	SCML1	Gain: 50	ZNF187	Gain: 55
CNTN4	Gain: 55	MBTPS2	Gain: 60	SCML2	Gain: 60	ZNF193	Gain: 55
DCLK3	Loss: 65	MDGA1	Loss: 85	SNCG	Loss: 70	ZNF197	Gain: 60
DDX1	Gain: 55	MITF*	Gain: 70	SNRK	Gain: 60	ZNF322A*	Gain: 50
DDX53	Gain: 60	MYCN	Gain: 55	SOX4	Gain: 70	ZNF35	Gain: 60
EDEM1	Gain: 50	NT5C1B	Gain: 55	SS18L2	Gain: 55	ZNF391	Gain: 50
EIF4E3	Gain: 70	NTSR2	Gain: 50	TMF1	Gain: 70	ZNF445	Gain: 60
ESD	Gain: 70	NUFIP1	Gain: 80	TNFSF11	Gain: 80	ZNF452	Gain: 50
FAM107A	Gain: 50	PAFAH1B1*	Gain: 70	TRPM6	Gain: 60	ZNF501	Gain: 60
FOXJ2	Loss: 50	PGBD1	Gain: 55	TSC22D1	Gain: 90	ZNF502	Gain: 60
FOXP1	Gain: 70	POLA1	Gain: 60	UBE1C*	Gain: 70	ZNF660	Gain: 60
GDF7	Gain: 55	PRL	Gain: 50	UBP1	Loss: 80	ZNF662	Gain: 60

^a The common cancer-related genes in both Asian and Caucasian are labeled with asterisk (*), and the detailed description of all genes is shown in Additional file 5: Table S4.

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ISSN: 1471-2407

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