Table 3 Chromosome imbalance regions with different alteration frequency in relation to tumor stages in lung cancer
Chromosome | Cytoband | Start site | End site | Size (Mb) | BAC number | Early stage (n=19) | Late Stage (n=21) | Difference in alteration frequency |
|---|---|---|---|---|---|---|---|---|
A. Asian | ||||||||
6 | p21.2 | 39548717 | 39877219 | 0.32 | 13 | 0 | Loss :62% | 62% |
6 | p22.3 | 21096443 | 22252887 | 1.15 | 39 | 0 | Gain :66% | 66% |
17 | p13.3 | 2443685 | 3461082 | 1.01 | 9 | Gain :21% | Gain :71% | 50% |
B. Caucasian | ||||||||
2 | p22.2-22.3 | 35262506 | 36832851 | 1.57 | 11 | 0 | Gain :100% | 100% |
2 | p25.1 | 8929622 | 11112217 | 2.18 | 16 | Gain :14% | Gain :100% | 86% |
3 | p24.1-24.3 | 23113657 | 26730485 | 3.62 | 32 | Loss : 7% | Loss :60% | 53% |
4 | p15.2 | 25955365 | 26477816 | 0.52 | 4 | 0 | Gain :60% | 60% |
10 | q24.2-24.3 | 100717385 | 104630288 | 3.91 | 44 | 0 | Loss :100% | 100% |