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Table 3 Association between body size and body composition with prostate cancer

From: Obesity, body composition, and prostate cancer

   Gleason 6 PC Gleason 7 PC Gleason 8-10 PC
Measure scale n OR 95% CI n OR 95% CI   OR 95% CI
BMI per kg/m2 402 0.989 0.964, 1.015 272 1.025 0.997, 1.055 135 1.039 1.000,1.081
  < 25 78 1.0 ref 55 1.0 ref 26 1.0 ref
  25-29.9 198 1.17 0.85, 1.61 116 1.12 0.75, 1.64 62 1.63 0.90, 2.91
  30-34.9 97 1.05 0.72, 1.51 66 1.24 0.80, 1.93 37 2.24 1.19, 4.23
  ≥ 35.0 29 0.96 0.57, 1.62 35 2.05 1.19, 1.93 10 1.41 0.54, 3.68
  ≥ 30 vs. < 30 (ref) 126 0.92 0.71, 1.19 101 1.33 0.98, 1.81 47 1.45 0.93, 2.25
WC per cm 402 0.994 0.984, 1.004 272 1.012 1.002, 1.022 135 1.016 0.999,1.033
  Q1 99 1.0 ref 66 1.0 ref 33 1.0 ref
  Q2 106 1.07 0.76, 1.49 60 0.98 0.65, 1.49 27 1.22 0.65, 2.29
  Q3 120 1.10 0.79, 1.53 75 1.18 0.79, 1.77 39 1.66 0.92, 2.98
  Q4 77 0.94 0.65, 1.35 70 1.46 0.95, 2.23 36 1.90 1.03, 3.53
  High vs. Low (ref) 197 1.00 0.78, 1.28 145 1.31 0.97, 1.75 75 1.59 1.04, 2.44
WHR per 0.1 unit 402 0.898 0.756, 1.066 272 1.232 1.029, 1.474 135 1.034 0.769,1.388
  Q1 100 1.0 ref 51 1.0 ref 29 1.0 ref
  Q2 112 0.99 0.71, 1.37 61 0.98 0.63, 1.51 37 1.04 0.57, 1.88
  Q3 85 0.85 0.60, 1.21 79 1.44 0.94, 2.20 24 0.88 0.47, 1.67
  Q4 105 0.86 0.61, 1.21 80 1.25 0.81, 1.92 45 1.11 0.61, 2.00
  High vs. Low (ref) 190 0.86 0.68. 1.10 159 1.36 1.01, 1.83 69 0.98 0.65, 1.49
FM per kg 402 0.993 0.981, 1.004 271 1.010 0.997, 1.024 135 1.020 1.004,1.037
  Q1 105 1.0 ref 63 1.0 ref 35 1.0 ref
  Q2 111 1.09 0.79, 1.51 67 1.17 0.77, 1.78 24 0.99 0.52, 1.88
  Q3 100 1.00 0.71, 1.39 67 1.34 0.88, 2.05 40 2.18 1.22, 3.87
  Q4 86 0.88 0.62, 1.25 75 1.52 1.00, 2.30 36 1.65 0.90, 3.03
  High vs. Low (ref) 186 0.90 0.71, 1.15 142 1.32 0.98, 1.77 76 1.93 1.25, 2.97
FFM per kg 402 1.006 0.991, 1.021 271 1.029 1.011, 1.048 135 1.047 1.021,1.074
  Q1 100 1.0 ref 78 1.0 ref 38 1.0 ref
  Q2 96 0.98 0.70, 1.38 63 1.01 0.68, 1.51 25 1.11 0.59, 2.06
  Q3 118 1.42 1.02, 1.99 60 1.16 0.76, 1.76 38 2.42 1.34, 4.39
  Q4 88 1.14 0.80, 1.64 71 1.72 1.14, 2.61 33 2.91 1.56, 5.44
  High vs. Low (ref) 206 1.31 1.02, 1.67 131 1.40 1.04, 1.89 71 2.50 1.60, 3.91
%BF per% 402 0.985 0.968, 1.004 272 1.002 0.980, 1.025 135 1.017 0.987, 1.048
  Q1 108 1.0 ref 60 1.0 ref 36 1.0 ref
  Q2 109 0.99 0.72, 1.38 68 1.29 0.85, 1.96 26 1.05 0.57, 1.93
  Q3 108 1.04 0.75, 1.44 84 1.63 1.08, 2.45 40 1.65 0.94, 2.92
  Q4 77 0.71 0.50, 1.02 60 1.07 0.70, 1.65 33 1.21 0.66, 2.19
  High vs. Low (ref) 185 0.88 0.69, 1.12 144 1.18 0.88, 1.58 73 1.39 0.92, 2.12
  1. All analyses adjusted for age (years), PSA (ng/ml), prostate volume (ml), race (white, non-white), family history (Yes, No/unsure), and current treatment for diabetes, CVD, BPH, or hyperlipidemia. Q = quartile. High vs Low defined at median value