Figure 6

miR-182 modulated the expression of MTSS1 and the cells invasive potential of HLF and HUH-1. A: the expression of MTSS1 was up-regulated in HLF and down-regulated in HUH-1 after transfection of anti-miR-182 and pre-miR-182, respectively. Cell invasion assay in HLF and HUH-1 cells were first transfected with anti-mir-182 and pre-mir-182, respectively or negative control and then subject to matrigel chamber assays, as described in Materials and Methods. After 24 h, invasion cells were counted after staining with crystal violet. *p < 0.05, **p < 0.01.