Estimation of groin recurrence risk in patients with squamous cell vulvar carcinoma by the assessment of marker gene expression in the lymph nodes

Table 4 The results of the comparison of Kaplan-Meier estimates for TTR for VC patients according to their LN gene expression levels

Transcript		TTR for patients with high expression level		TTR for patients with low expression level	P
	Cut-off Value	Median TTR (months)	HR; CI	Median TTR (months)
SFN	0.4815	8.7	0.21; 95% CI, 0.06-0.86	not reached	0.029
CA12	0.23	6.9	0.16; 95% CI, 0.04-0.61	not reached	0.008
JUP	0.4815	6.89	0.18; 95% CI, 0.05-0.74	not reached	0.016
CSTA	0.03	6.89	0.17; 95% CI, 0.04-0.66	not reached	0.011

Abbreviations: TTR – time to groin recurrence; HR – hazard ratio; CI – confidence interval; Cut-off Value - the arbitrarily chosen cut-off for gene expression value used for patient stratification; P – P value calculated with the use of the log-rank test.

ISSN: 1471-2407