Estimation of groin recurrence risk in patients with squamous cell vulvar carcinoma by the assessment of marker gene expression in the lymph nodes

Table 2 Significant Gene Ontology categories overrepresented among differentially expressed genes

GO category	GO term	Exp. No.	P	Pa
GO:0007155	cell adhesion	28.3	1,52E-09	2,07E-06
GO:0008544	epidermis development	2.7	6,70E-09	4,54E-06
GO:0032502	developmental process	22.2	1,85E-06	0,000837
GO:0007275	multicellular organismal development	80.8	2,74E-06	0,000928
GO:0048730	epidermis morphogenesis	1.5	1,15E-05	0,00311
GO:0030216	keratinocyte differentiation	1.0	3,35E-05	0,006311
GO:0007626	locomotory behavior	7.2	3,45E-05	0,006311
GO:0006954	inflammatory response	11.6	3,72E-05	0,006311

Abbreviations: GO – Gene Ontology; Exp. No. - the expected number of differentially expressed genes (probesets) to be found among genes annotated to each GO term; P - P value; Pa - adjusted P value.

ISSN: 1471-2407