Figure 5From: RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls Serum microvesicle RNA from patients with glioblastoma multiforme has an overabundance of RNA with size <500 nt. (A) Gene expression relative to the amount of microvesicle RNA present in serum of GBM patients and normal healthy controls. Bars represent the average expression of 16 genes as measured by qRT-PCR, normalized to the amount of exoRNA isolated from 1 mL of serum. The yield from GBM samples is higher than from controls, but this does not result in higher gene expression. (B) From the Bioanalyzer profiles it appears that the extra RNA in GBM serum is predominantly <300 nt. The plot is showing the mean ± SEM (N = 10 GBM and 10 controls). The non-visible parts of the profiles (>500 nt) were very similar for GBM and controlsBack to article page