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Table 1 Correlation of CGCG (−695~-692) methylaton with case characteristics

From: Promoter hypermethylation-induced transcriptional down-regulation of the gene MYCT1in laryngeal squamous cell carcinoma

 

Case (n)

Positve (n)

Negative (n)

P

Sample

    

Cancer tissue

73

59

14

P<0.01

Paired normal tissue

73

13

60

 

Age at surgery

    

 <60

35

28

7

0.864

 >60

38

31

7

 

Gender

    

 Male

58

47

11

0.928

 Female

15

12

3

 

Histological classification

    

 Poorly differentiated

49

46

3

P<0.01

 Well differentiated

24

13

11

 

T classification

    

 T1

13

10

3

0.980

 T2

26

21

5

 

 T3

28

23

5

 

 T4

6

5

1

 

Lymph node metastasis

    

 Negative

55

44

11

0.755

 Positive

18

15

3

 

Distant metastasis

    

 Negative

69

56

13

0.761

 Positive

4

3

1

 

Clinical stage

    

 I

13

9

4

0.533

 II

22

17

5

 

 III

30

26

4

 

 IV

8

7

1

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