Table 2 Associations between demographic and clinical data of patients and methylation of five genes
From: MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma
Characteristic | n | MGMT | GATA6 | CD81 | CASP8 | DR4 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
U (%) | M (%) | P | U (%) | M (%) | P | U (%) | M (%) | P | U (%) | M (%) | P | U (%) | M (%) | P | ||
Age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
<60 years | 32 | 14.5 | 27.6 | 0.039 | 15.8 | 26.3 | 0.454 | 22.4 | 19.7 | 1.000 | 28.0 | 14.7 | 0.002 | 26.7 | 14.7 | 0.477 |
≥60 years | 44 | 34.2 | 23.7 |  | 15.8 | 42.1 |  | 31.6 | 26.3 |  | 16.0 | 41.3 |  | 32.0 | 26.7 | |
Sex | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Male | 30 | 56.7 | 43.3 | 0.348 | 33.3 | 66.7 | 0.806 | 53.3 | 46.7 | 1.000 | 37.9 | 62.1 | 0.477 | 50.0 | 50.0 | 0.239 |
Female | 46 | 43.5 | 56.5 | Â | 30.4 | 69.6 | Â | 54.3 | 45.7 | Â | 47.8 | 52.2 | Â | 64.4 | 34.6 | |
Survival | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
<36 months | 62 | 56.5 | 43.5 | 0.006 | 30.6 | 69.4 | 0.775 | 54.8 | 45.2 | 0.774 | 37.7 | 62.3 | 0.035 | 53.2 | 46.8 | 0.061 |
≥36 months | 14 | 14.3 | 85.7 |  | 35.7 | 64.3 |  | 50.0 | 50.0 |  | 71.4 | 28.6 |  | 84.6 | 15.4 | |