Table 5 Antioxidant micronutrients from food and supplements and ovarian cancer risk

Vitamin C

Food (mg)

1 (<82.3)

75

127

1.00

1.00

2 (82.3-141.7)

72

132

0.93

0.58-1.48

1.08

0.65-1.79

3 (>141.8)

58

128

0.99

0.59-1.67

1.29

0.72-2.29

p for trend

0.75

0.89

Supplements

No

56

111

1.00

1.00

Yes

149

276

1.34

0.87-2.06

1.63

1.01-2.62

Combined food and supplements (mg)

1 (<147.5)

74

128

1.00

1.00

2 (147.5-458.6)

72

132

1.09

0.69-1.74

1.38

0.83-2.31

3 (>458.7)

59

127

1.06

0.66-1.71

1.42

0.84-2.40

p for trend

0.72

0.28

Vitamin E

Food (aTE)

1 (<7.4)

69

128

1.00

1.00

2 (7.4-11.5)

64

132

0.96

0.56-1.65

0.94

0.53-1.67

3 (>11.6)

72

127

1.04

0.55-1.98

0.89

0.45-1.77

p for trend

0.84

0.89

Supplements

No

58

114

1.00

1.00

Yes

147

273

1.35

0.88-2.07

1.63

1.02-2.63

Combined food and supplements (aTE)

1 (<21.7)

69

128

1.00

1.00

2 (21.7-114.8)

88

131

1.53

0.98-2.41

1.81

1.10-1.04

3 (>114.9)

48

128

0.87

0.52-1.42

1.03

0.59-1.78

p for trend

0.29

0.10

Beta-carotene

Food (mcg)

1 (<2,070)

67

128

1.00

1.00

2 (2,070-3,675)

66

132

1.14

0.70-1.86

1.05

0.61-1.78

3 (>3,676)

72

127

1.35

0.81-2.25

1.45

0.83-2.52

p for trend

0.61

0.91

Supplements

No

67

138

1.00

1.00

Yes

138

249

1.40

0.93-2.11

1.69

1.08-2.66

Combined food and supplements (mcg)

1 (<3,040)

79

128

1.00

1.00

2 (3,040-5,075)

57

132

0.82

0.51-1.33

0.87

0.52-1.47

3 (>5,076)

69

127

1.09

0.67-1.79

1.38

0.80-2.35

p for trend

0.33

0.41

Selenium

Food (mcg)

1 (<59.5)

84

128

1.00

1.00

2 (59.5-87.7)

58

132

0.48

0.28-0.81

0.55

0.31-0.98

3 (>87.8)

63

127

0.40

0.21-0.78

0.41

0.20-0.85

p for trend

0.01

0.10

Supplements

No

69

148

1.00

1.00

Yes

136

239

1.44

0.95-2.15

1.64

1.05-2.56

Combined food and supplements (mcg)

1 (<72.4)

79

128

1.00

1.00

2 (72.4-103.6)

58

132

0.69

0.42-1.16

0.73

0.42-1.27

3 (>103.7)

68

127

0.73

0.40-1.30

0.75

0.39-1.43

p for trend

0.20

0.30

Lutein

Food (mcg)

1 (<1,019)

65

128

1.00

1.00

2 (1,019-1,882)

65

131

1.21

0.74-1.97

1.28

0.75-2.19

3 (>1,882)

75

128

1.46

0.89-2.39

1.54

0.90-2.62

p for trend

0.63

0.51

Lycopene

Food (mcg)

1 (<2,504)

51

127

1.00

1.00

2 (2,504-5,464)

83

133

1.68

1.01-2.79

1.43

0.83-2.47

3 (>5,465)

71

127

1.58

0.91-2.74

1.48

0.82-2.68

p for trend

0.05

0.26