From: Total and individual antioxidant intake and risk of epithelial ovarian cancer
 | Cases (n  = 205) n (%) | Controls (n  = 391) n (%) | OR (95 % CI)* | ||
---|---|---|---|---|---|
Education | |||||
  High school or less | 61 | (29.8) | 133 | (34.0) | 1.00 (Ref) |
  College | 93 | (45.4) | 159 | (40.7) | 0.90 (0.59-1.38) |
  Graduate school | 51 | (24.9) | 99 | (25.3) | 0.76 (0.47-1.24) |
Race/ethnicity | |||||
  White | 179 | (87.3) | 344 | (88.4) | 1.00 (Ref) |
  Black | 9 | (4.4) | 17 | (4.4) | 1.02 (0.42-2.44) |
  Other | 8 | (3.9) | 17 | (4.4) | 0.82 (0.33-1.99) |
  Hispanic (any race) | 9 | (4.4) | 11 | (2.8) | 1.13 (0.44-2.92) |
BMI | |||||
  Underweight (<18.5) | 1 | (0.5) | 1 | (0.3) | 1.02 (0.06-17.31) |
  Normal (18.5-25) | 90 | (43.9) | 180 | (46.4) | 1.00 (Ref) |
  Overweight (25–29.9) | 54 | (26.3) | 122 | (31.4) | 1.07 (0.69-1.65) |
  Obese (30–34.9) | 36 | (17.6) | 59 | (15.2) | 1.39 (0.83-2.32) |
  Very obese (>35) | 24 | (11.7) | 26 | (6.7) | 1.54 (0.81-2.89) |
Parity | |||||
  0 – 1 | 97 | (47.3) | 92 | (23.5) | 1.00 (Ref) |
  2 | 60 | (29.3) | 137 | (35.0) | 0.45 (0.29-0.69) |
  >3 | 48 | (23.4) | 162 | (41.4) | 0.42 (0.26-0.66) |
Smoking status | |||||
  Never | 108 | (52.7) | 204 | (52.2) | 1.00 (Ref) |
  Past | 78 | (38.1) | 149 | (38.1) | 1.12 (0.76-1.64) |
  Current | 19 | (9.3) | 38 | (9.7) | 0.87 (0.46-1.62) |
Oral contraceptive use | |||||
  Never | 85 | (41.5) | 193 | (49.4) | 1.00 (Ref) |
  Ever | 120 | (58.5) | 198 | (50.6) | 0.88 (0.61-1.28) |
Use of HRT | |||||
  Never | 159 | (77.6) | 285 | (72.9) | 1.00 (Ref) |
  Unopposed E only | 22 | (10.7) | 34 | (8.7) | 1.56 (0.86-2.84) |
  Any combined HRT | 24 | (11.7) | 72 | (18.4) | 0.63 (0.38-1.06) |
Age at menarche | |||||
  >13 | 41 | (20.1) | 99 | (25.4) | 0.81 (0.51-1.27) |
  12-13 | 117 | (57.4) | 200 | (51.3) | 1.00 (Ref) |
  <11 | 46 | (22.6) | 91 | (23.3) | 0.75 (0.48-1.17) |
Menopause status | |||||
  Premenopausal | 71 | (34.6) | 49 | (12.5) | 1.51 (0.85-2.69) |
  Postmenopausal | |||||
  Age at menopause | |||||
  <40 | 5 | (2.4) | 14 | (3.6) | 0.77 (0.26-2.31) |
  41-54 | 86 | (42.0) | 239 | (61.3) | 1.00 (Ref) |
  >55 | 12 | (5.9) | 37 | (9.5) | 0.99 (0.48-2.01) |
  Unknown | 31 | (15.1) | 52 | (13.3) | 1.52 (0.91-2.56) |
Tubal Ligation | |||||
  No | 175 | (85.4) | 315 | (80.6) | 1.00 (Ref) |
  Yes | 30 | (14.6) | 76 | (19.4) | 0.59 (0.36-0.94) |
First relative with ovarian cancer | |||||
  No | 195 | (95.1) | 377 | (96.4) | 1.00 (Ref) |
  Yes | 10 | (4.9) | 14 | (3.6) | 1.32 (0.55-3.17) |