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Table 1 Immunohistochemical analysis

From: Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation

  Control Intermittent HBO Daily HBO
Angiogenesis (numbers/mm2) 79.9 ± 18.7Δ 41.8 ± 17.1*Δ 79.2 ± 16.2
Proliferation
(% Ki67-positive cells)
21.7 ± 17.6 26.5 ± 17.9 21.4 ± 7.8
Cell death
(% of total area)
7.6 ± 4.1 7.8 ± 1.3 5.8 ± 0.8
  1. Angiogenesis (CD31), proliferation (Ki67) and cell death (TUNEL) stained in tumors from untreated controls and after intermittent and daily hyperbaric oxygen treatment (HBO). n = 5 in all groups. Mean values ± SD. *p < 0.02 compared to both control and daily HBO treatment. Δresults obtained from Jevne et al. [21]