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Table 3 Genes linked to genomic instability

From: Effects on human transcriptome of mutated BRCA1 BRCT domain: A microarray study

Biological Process Gene Symbol Gene Name Contrast log2 (Fold Change)
DNA damage response and repair downregulation EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 A1789TvsWT −0.4309041
  SMC1A structural maintenance of chromosomes 1A A1789TvsWT MutvsWT −0.2754507 −0.2640263
  PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme A1789TvsWT −0.4286825
  AHNAK AHNAK nucleoprotein A1789TvsWT M1775RvsWT MutvsWT −0.3988113
     −0.3103867
     −0.3940570
  SOD2 superoxide dismutase 2, mitochondrial M1775RvsWT MutvsWT −0.3376169
     −0.2502831
DNA damage response and repair upregulation MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) A1789TvsWT 0.3293561
  TERF1 telomeric repeat binding factor (NIMA-interacting) 1 MutvsWT 0.2790907
  OBFC2A oligonucleotide/oligosaccharide-binding fold containing 2A M1775RvsWT 0.3666172
  OBFC2B oligonucleotide/oligosaccharide-binding fold containing 2B A1789TvsWT MutvsWT 0.4070777
     0.3417360