Figure 5
From: Mifepristone prevents repopulation of ovarian cancer cells escaping cisplatin-paclitaxel therapy
Mifepristone (MF) enhances the therapeutic efficacy of cisplatin (CDDP) and paclitaxel (PTX) as shown by comparative dose response curves. Cells were treated with CDDP for 1 h (A and C), PTX for 3 h (B and C), and exposed or not exposed to 10 μM MF for 7 days (A-C). Cell growth (A and B) was calculated considering controls as 100%. In (C), relative growth was assessed by considering 1 the number of cells at the beginning of the experiment. The dashed lines represent 50% of the growth depicted by control, untreated cells after 7 days of incubation.