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Table 4 Relative risk of second breast cancer vs. selected risk variables

From: Risk of second breast cancer in female Hodgkin’s lymphoma survivors: a meta-analysis

Variable RR (95% CI)
Mediastinal mass +  
Wahner-Roedler 2003 [44] 4.22 (2.71, 6.57)
Alm El-Din 2009 [54] 11.46 (6.78, 19.38)
Mediastinal mass -  
Wahner-Roedler 2003 [44] 1.70 (0.79, 3.63)
Alm El-Din 2009 [54] 6.09 (2.37, 15.67)
Splenectomy +  
Wolden 1998 [30] 2.10 (0.62, 7.16)
Wahner-Roedler 2003 [44] 4.70 (2.87, 7.69)
Alm El-Din 2009 [54] 9.86 (5.42, 17.92)
Splenectomy -  
Wahner-Roedler 2003 [44] 1.90 (1.05, 3.45)
Alm El-Din 2009 [54] 9.67 (4.87, 19.20)
Mantle RT, no pelvic RT  
De Bruin 2009 [55] 8.20 (6.62, 10.15)
Mediastinal RT, no pelvic RT  
De Bruin 2009 [55] 3.71 (1.38, 9.97)
Mantle RT + pelvic RT  
De Bruin 2009 [55] 2.70 (1.11, 6.56)
ER-/PR-  
Dores 2010 [57] 9.30 (7.00, 12.36)
ER+/PR+  
Dores 2010 [57] 4.95 (3.84, 6.39)
  1. CI confidence interval, ER estrogen receptors, PR progesterone receptors, RR relative risk, RT radiotherapy.
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