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Table 6 Results of quantitative studies comparing different patient groups

From: A systematic review of the impact of stigma and nihilism on lung cancer outcomes

Study

Participants

Outcome

Main findings

Lung (N = 96) vs breast (N = 30) or prostate (N = 46) cancer patients

LoConte 2008: Else-Quest 2009 USA

  

Baseline differences between groups

Stage IV

Patient

 

Lung cancer patients

Guilt and shame (SSGS)

NS^

100% NSCLC

Shame subscale

NS^

Perceived cancer related stigma (5 items)

p < 0.01^ greater for those with lung cancer

Lung (N = 89) vs breast (N = 30) vs prostate (N = 43) cancer patients

LoConte 2008: Else-Quest 2009

USA

  

Baseline differences between groups

Stage IV

Patient

 

Lung cancer patients

Guilt and shame (SSGS)

NS^^

100% NSCLC

Perceived stigma (single item)

NS^^

Smoking history (N = 88) vs Never smoker (N = 8) lung cancer patients

LoConte 2008: Else-Quest 2009 USA

  

Differences between groups

Stage IV NSCLC

Patient

 
 

Guilt and shame (SSGS)

p = 0.02* greater for those with a smoking history

Perceived cancer related stigma (5 items)

NR

Current smoker (N = 25) vs Former smoker (N = 66) vs Never smoker (N = 9) lung cancer patients

Lobchuk 2008b Canada

58% diagnosed with

Patient

Differences between groups

advanced disease 76% NSCLC

Primary caregiver blame re patient’s efforts to control the disease - single item

p < 0.05^^ greater for current vs never smokers

p < 0.05^^ greater for former vs never smokers

Lung vs breast cancer

Wassenaar 2007 USA

 

Physician

Differences between groups

Different stages

Referrals to clinical oncologist for the scenarios:

 

after surgery for stage 1B disease

p = 0.86*

hepatic and lung metastases – good performance status

p < 0.001* lower for lung cancer

metastases - poor performance status

p < 0.001* lower for lung cancer

advanced disease – solely for supportive or palliative care

p = 0.009* higher for lung cancer

Reported importance of type of cancer as a factor contributing to decision to refer to oncologist

p = 0.19#

Belief that chemotherapy could improve survival for:

 

stage IB resected disease

p = 0.001* lower for lung cancer

metastatic disease – good performance status

p = 0.015* lower for lung cancer

  1. ECOG = Eastern Co-operative Oncology Group; NSCLC = Non small cell lung cancer; SCLC = Small cell lung cancer; SSGS = State Shame and Guilt Scale; NR = Not reported; NS = Not statistically significantly different; ^ MANCOVA with sex, age and time since diagnosis taken into account; ^^ Univariate ANOVA; * 2-sided t test: * Chi-squared or Fisher’s exact test: # Non parametric Wilcoxon rank sum test.