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Table 4 Incidence rate ratio (IRR) for colorectal cancer for tertiles of intake of dietary fibre by IL10 polymorphisms among cases (N c ) and subcohort (N s )

From: Interaction between interleukin-10 (IL-10) polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study

  Intake of dietary fibre IRR (95% CI)a  
1.tertile 2.tertile 3.tertile Intake tertiles (g/day)  
  Nc Ns Nc Ns Nc Ns <17.0 17.0-22.7 >22.7 PInt b
rs3024505
CC 96 152 86 176 86 225 1.00 0.87 (0.65-1.16) 0.73 (0.55-0.98)  
CT and TT 28 56 39 82 43 84 0.83 (0.54-1.27) 0.83 (0.58-1.18) 0.96 (0.66-1.38) 0.16
C-592A (rs1800872)
CC 69 137 81 148 88 185 1.00 1.17 (0.84-1.61) 1.08 (0.78-1.49)  
AC and AA 55 71 44 110 41 124 1.44 (1.02-2.05) 0.87 (0.59-1.27) 0.80 (0.54-1.19) 0.02
  1. a Analysis adjusted for smoking status, alcohol, HRT status (women only), BMI, use of NSAID, and intake of red and processed meat.
  2. b P-value for interaction between polymorphisms and dietary factors for the adjusted estimates.