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Table 4 Incidence rate ratio (IRR) for colorectal cancer for tertiles of intake of dietary fibre by IL10 polymorphisms among cases (N c ) and subcohort (N s )

From: Interaction between interleukin-10 (IL-10) polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study

 

Intake of dietary fibre

IRR (95% CI)a

 

1.tertile

2.tertile

3.tertile

Intake tertiles (g/day)

 
 

Nc

Ns

Nc

Ns

Nc

Ns

<17.0

17.0-22.7

>22.7

PInt b

rs3024505

CC

96

152

86

176

86

225

1.00

0.87 (0.65-1.16)

0.73 (0.55-0.98)

 

CT and TT

28

56

39

82

43

84

0.83 (0.54-1.27)

0.83 (0.58-1.18)

0.96 (0.66-1.38)

0.16

C-592A (rs1800872)

CC

69

137

81

148

88

185

1.00

1.17 (0.84-1.61)

1.08 (0.78-1.49)

 

AC and AA

55

71

44

110

41

124

1.44 (1.02-2.05)

0.87 (0.59-1.27)

0.80 (0.54-1.19)

0.02

  1. a Analysis adjusted for smoking status, alcohol, HRT status (women only), BMI, use of NSAID, and intake of red and processed meat.
  2. b P-value for interaction between polymorphisms and dietary factors for the adjusted estimates.
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BMC Cancer

ISSN: 1471-2407

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