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Table 2 Incidence rate ratios and 95% confidence intervals for the studied IL10 gene polymorphisms in the diet, cancer and health study

From: Interaction between interleukin-10 (IL-10) polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study

  NCase NSubcohort Crude IRR (95% CI)a Adjusted IRR (95% CI)b P-valuec
rs3024505
CC 268 553 1.00 1.00 -
CT 99 202 0.99 (0.79-1.25) 1.01 (0.80-1.28) 0.91
TT 11 20 1.15 (0.63-2.10) 1.11 (0.61-2.03) 0.73
CT and TT 110 222 1.01 (0.81-1.26) 1.02 (0.82-1.28) 0.85
C-592A (rs1800872)d
CC 238 470 1.00 1.00 -
AC 116 261 0.91 (0.73-1.14) 0.90 (0.72-1.12) 0.36
AA 24 44 1.11 (0.74-1.67) 1.10 (0.73-1.65) 0.65
AC and AA 140 305 0.94 (0.77-1.16) 0.93 (0.76-1.14) 0.50
  1. a Crude analyses.
  2. b Analyses adjusted for smoking status, alcohol, HRT status (women only), BMI, use of NSAID, and intake of red and processed meat and dietary fibre.
  3. c P-value for the adjusted estimates.
  4. dData for IL10 rs1800872 were taken from (38).