| |
NCase
|
NSubcohort
|
Crude IRR (95% CI)a
|
Adjusted IRR (95% CI)b
|
P-valuec
|
|---|
|
rs3024505
|
|
CC
|
268
|
553
|
1.00
|
1.00
|
-
|
|
CT
|
99
|
202
|
0.99 (0.79-1.25)
|
1.01 (0.80-1.28)
|
0.91
|
|
TT
|
11
|
20
|
1.15 (0.63-2.10)
|
1.11 (0.61-2.03)
|
0.73
|
|
CT and TT
|
110
|
222
|
1.01 (0.81-1.26)
|
1.02 (0.82-1.28)
|
0.85
|
|
C-592A (rs1800872)d
|
|
CC
|
238
|
470
|
1.00
|
1.00
|
-
|
|
AC
|
116
|
261
|
0.91 (0.73-1.14)
|
0.90 (0.72-1.12)
|
0.36
|
|
AA
|
24
|
44
|
1.11 (0.74-1.67)
|
1.10 (0.73-1.65)
|
0.65
|
|
AC and AA
|
140
|
305
|
0.94 (0.77-1.16)
|
0.93 (0.76-1.14)
|
0.50
|
-
a Crude analyses.
-
b Analyses adjusted for smoking status, alcohol, HRT status (women only), BMI, use of NSAID, and intake of red and processed meat and dietary fibre.
-
c P-value for the adjusted estimates.
-
dData for IL10 rs1800872 were taken from (38).
