A population-based cohort study of chest x-ray screening in smokers: lung cancer detection findings and follow-up

BMC Cancer

Table 2 Characteristics of lung cancer (LC) patients in the cohort and in the control group

	Patients with LC
	Cohort (n = 245)	Control Group (n = 156)	P
Age, median (IQR)	68 (60-73)	68 (62-73)	0.930
Male/female (ratio)	221/24 (9.2)	144/12 (12.0)	0.472
Pack-years, median (IQR)	49 (36-66)^a	45 (30-67)^b	0.598
*Asymptomatic LC diagnosis, n (%)**	67 (27.3%)	27 (18.6%)^c	0.051
Histologically confirmed LC, n (%)	211 (86%)	131(84%)
Adenocarcinoma, n (%)	69 (33%)	36 (27%)
Squamous cell carcinoma, n (%)	82 (39%)	64 (49%)	0.411
Other NSCLC, n (%)	31 (15%)	14 (11%)
SCLC, n (%)	29 (14%)	17 (13%)
Stage of LC at diagnosis ^{d, e}
I, n (%)	49 (21%)	23 (15%)
II, n (%)	13 (6%)	9 (6%)
IIIA, n (%)	30 (13%)	20 (13%)	0.433
IIIB-IV and extensive SCLC, n (%)	136 (60%)	102 (66%)
Follow-up months, median (range)^f	101 (49-161)	123 (119-131)	0.232

LC: lung cancer; IQR: interquartile range; NSCLC: non-small cell lung cancer; SCLC: small cell lung cancer
*In nonparticipants of the cohort and in the control group the asymptomatic LCs diagnosed were all incidentally found, as documented by patient file review
^aNot available in 28 patients
^bNot available in 41 patients
^cNot available in 11 patients
^dNot available in 17 patients of Cohort
^eNot available in 2 patients of Control Group
^fCalculated in survivors at end of study

ISSN: 1471-2407