Figure 7From: Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition Profile changes of in vitro KPL-4 cells compared to circulating KPL-4 cells out of tumour bearing animals. Samples were analysed using RT2 Profiler PCR Array System focusing on EMT specific genes. Data analyses shows that COL5A2, EGFR, MSN, PDGFRB and Twist were upregulated on CTCs whereas downregulation of CK-19 and SPP1 could be observed (n = 5).Back to article page